Calpain small subunit 1 / DyLight 488 / 1D11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-59446G (View supplier product page)
Size 100 μl
Price $499.00
Antigen Calpain small subunit 1
Clone 1D11
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 488
Target Species Human
Applications WB, ELISA, ICC/IF
Description Calpain small subunit 1 Antibody (1D11) [DyLight 488]
About Calpain small subunit 1 and DyLight 488
Calpain small subunit 1 This gene is a member of the calpain small subunit family. Calpains are calcium-dependent cysteine proteinases that are widely distributed in mammalian cells. Calpains operate as heterodimers, comprising a specific large catalytic subunit (calpain 1 subunit in Calpain I, and calpain 2 subunit in Calpain II), and a common small regulatory subunit encoded by this gene. This encoded protein is essential for the stability and function of both calpain heterodimers, whose proteolytic activities influence various cellular functions including apoptosis, proliferation, migration, adhesion, and autophagy. Calpains have been implicated in neurodegenerative processes, such as myotonic dystrophy. A pseudogene of this gene has been defined on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra