AIPL1 / DyLight 680 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-76953FR (View supplier product page)
Size 100 μl
Price $499.00
Antigen AIPL1
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 680
Target Species Human, Mouse
Applications WB, ELISA, IHC, ICC/IF, IHC-P
Description AIPL1 Antibody [DyLight 680]
About AIPL1 and DyLight 680
AIPL1 Leber congenital amaurosis (LCA) is the most severe inherited retinopathy with the earliest age of onset and accounts for at least 5% of all inherited retinal diseases. Affected individuals are diagnosed at birth or in the first few months of life with nystagmus, severely impaired vision or blindness and an abnormal or flat electroretinogram. The photoreceptor/pineal-expressed gene, AIPL1, encoding aryl-hydrocarbon interacting protein-like 1, is located within the LCA4 candidate region. The encoded protein contains three tetratricopeptide motifs, consistent with chaperone or nuclear transport activity. Mutations in this gene may cause approximately 20% of recessive LCA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
DyLight 680 DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 680 Excitation and Emission Spectra