ABCG2 / Alexa Fluor 647 / 3G8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22124AF647 (View supplier product page)
Size 100 μl
Price $469.00
Antigen ABCG2
Clone 3G8
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human, Mouse, Primate
Applications WB, FC, ELISA, IHC, ICC/IF, IHC-P
Description ABCG2/CD338 Antibody (3G8) [Alexa Fluor® 647]
About ABCG2 and Alexa Fluor 647
ABCG2 The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra