14-3-3 epsilon / DyLight 350 / 4F8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-59395UV (View supplier product page)
Size 100 μl
Price $499.00
Antigen 14-3-3 epsilon
Clone 4F8
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 350
Target Species Human
Applications WB, ELISA, ICC/IF
Description 14-3-3 epsilon Antibody (4F8) [DyLight 350]
About 14-3-3 epsilon and DyLight 350
14-3-3 epsilon This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra