ATM Polyclonal / DyLight 488 /

Product Details
Supplier Thermo Fisher Scientific
Catalog #: PA5-22690 (View supplier product page)
Size 50 μl
Price $446.00
Antigen ATM
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 488
Target Species Canine, Human, Marsupial, Mouse, Rat
Applications ELISA, FC, IHC, IHC-P, WB
Description ATM Polyclonal Antibody, DyLight 488
About ATM and DyLight 488
ATM The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra