Perforin / Pacific Blue / S16009B

Product Details
Supplier BioLegend
Catalog #: 154407 (View supplier product page)
Size 25 μg
Price $159.00
Antigen Perforin
Clone S16009B
Host Rat
Isotype IgG2a κ
Conjugate Pacific Blue
Target Species Mouse
Applications ICS
Description Pacific Blue anti-mouse Perforin
About Perforin and Pacific Blue
Perforin This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017]
Pacific Blue Pacific Blue® (Pac Blue, PacBlue) is a blue-emitting organic fluorophore that can be excited by the 405 nm Violet laser and captured with a 450/50 nm bandpass filter. Pacific Blue has an excititaion peak at 401 nm and an emission peak at 452 nm.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Pacific Blue Excitation and Emission Spectra