Fibroblast Activation Protein alpha / Alexa Fluor 750 / FAP/4853
Fibroblast Activation Protein alpha / Alexa Fluor 750 / FAP/4853
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP3-14220AF750 (View supplier product page) | |
Size | 100 μl | |
Price | $519.00 | |
Antigen | Fibroblast Activation Protein alpha | |
Clone | FAP/4853 | |
Host | Mouse | |
Isotype | IgG2c κ | |
Conjugate | Alexa Fluor 750 | |
Target Species | Human | |
Applications | IHC, IHC-P | |
Description | Fibroblast Activation Protein alpha/FAP Antibody (FAP/4853) [Alexa Fluor® 750] |
About Fibroblast Activation Protein alpha and Alexa Fluor 750
Fibroblast Activation Protein alpha | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] | |
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Alexa Fluor 750 | Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications. |
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