Fibroblast Activation Protein alpha / Alexa Fluor 647 / FAP/4851
Fibroblast Activation Protein alpha / Alexa Fluor 647 / FAP/4851
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP3-14219AF647 (View supplier product page) | |
Size | 100 μl | |
Price | $519.00 | |
Antigen | Fibroblast Activation Protein alpha | |
Clone | FAP/4851 | |
Host | Mouse | |
Isotype | IgG2c κ | |
Conjugate | Alexa Fluor 647 | |
Target Species | Human | |
Applications | IHC, IHC-P | |
Description | Fibroblast Activation Protein alpha/FAP Antibody (FAP/4851) [Alexa Fluor® 647] |
About Fibroblast Activation Protein alpha and Alexa Fluor 647
Fibroblast Activation Protein alpha | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014] | |
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Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
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