CD71 Monoclonal / DyLight 755 / 66IG10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34542IR (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen CD71
Clone 66IG10
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 755
Target Species Human
Applications WB, FC, IHC-Fr, ICC/IF, ELISA, IHC
Description It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Its epitope is localized in the extracellular domain of CD71. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.
About CD71 and DyLight 755
CD71 This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra