MAPK1 / Janelia Fluor 549 / PCRP-MAPK1-1D1

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-14157JF549 (View supplier product page)
Size 100 μl
Price $519.00
Antigen MAPK1
Clone PCRP-MAPK1-1D1
Host Mouse
Isotype IgG2b
Conjugate Janelia Fluor 549
Target Species Human
Applications FC, ELISA, ICC/IF
Description ERK2 Antibody (PCRP-MAPK1-1D1) [Janelia Fluor® 549]
About MAPK1 and Janelia Fluor 549
MAPK1 This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra