CD11b Monoclonal / Brilliant Ultraviolet 615 / ICRF44

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 366-0118-42 (View supplier product page)
Size 100 Tests
Price $411.00
Antigen CD11b
Clone ICRF44
Host Mouse
Isotype IgG1 κ
Conjugate Brilliant Ultraviolet 615
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description CD11b Monoclonal Antibody (ICRF44), Brilliant Ultra Violet 615, eBioscience
About CD11b and Brilliant Ultraviolet 615
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Brilliant Ultraviolet 615 BD Horizon Brilliant™ UltraViolet 615 (BUV615) is a tandem dye has an excitation peak at 348 nm and has an emission maximum of 616 nm. This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 615 Excitation and Emission Spectra