CD11b / NovaFluor Red 710 / ICRF44

Product Details
Supplier Thermo Fisher Scientific
Catalog #: H036T03R04 (View supplier product page)
Size 100 Tests
Price $395.00
Antigen CD11b
Clone ICRF44
Host Mouse
Isotype IgG1 κ
Conjugate NovaFluor Red 710
Target Species Baboon, Chimpanzee, Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description CD11b Monoclonal Antibody (ICRF44), NovaFluor™ Red 710, eBioscience™
About CD11b and NovaFluor Red 710
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
NovaFluor Red 710 The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliant™ family of fluorescent polymers from BD. NovaFluor Red 710 has an excitation peak at 637 nm and an emission peak at 710 nm.
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NovaFluor Red 710 Excitation and Emission Spectra