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CD86 mFluor Red 780 (GL-1, Rat) - Reactivity: Mouse
Product Details
| Description | Anti-Mouse Cd86 (GL-1) ColorWheel Dye-Ready mAb - | |
|---|---|---|
| Conjugate | mFluor Red 780 | |
| Clone | GL-1 | |
| Target Species | Mouse | |
| Applications | ||
| Supplier | MilliporeSigma | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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| Price | ||
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About CD86
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
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