CD35 / mFluor Violet 540 / E11

Product Details
Supplier MilliporeSigma
Catalog #: CWA-1024-25UL+CWDS-MF540-25UL (View supplier product page)
Size 25 μl
Price $194.90
Antigen CD35
Clone E11
Host Mouse
Isotype IgG1
Conjugate mFluor Violet 540
Target Species Human, Non-Human Primate
Applications
Description Anti-Human CD35 (E11) ColorWheel Dye-Ready mAb
About CD35 and mFluor Violet 540
CD35 This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]
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mFluor Violet 540 Excitation and Emission Spectra