CD4 Spark Blue 574 (SK3, Mouse) - Reactivity: Human
Product Details
| Description | Spark Blue 574 anti-human CD4 | |
|---|---|---|
| Conjugate | Spark Blue 574 | |
| Clone | SK3 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | BioLegend | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About Spark Blue 574
Spark Blue™ 574 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 506 nm and an emission peak at 574 nm. This fluorophore is an alternative to Alexa Fluor™ 532 and can be efficiently excited by the 488 nm laser and can be unmixed from FITC and PE.
Spark Blue™ 574 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 506 nm and an emission peak at 574 nm. This fluorophore is an alternative to Alexa Fluor™ 532 and can be efficiently excited by the 488 nm laser and can be unmixed from FITC and PE.
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