CD8a StarBright Violet 475 (LT8, Mouse) - Reactivity: Human
Product Details
| Description | Mouse anti Human CD8:StarBright Violet 475 | |
|---|---|---|
| Conjugate | StarBright Violet 475 | |
| Clone | LT8 | |
| Target Species | Human | |
| Applications | FC | |
| Supplier | Bio-Rad | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
About StarBright Violet 475
StarBright Violet 475 (SBV475) is a fluorescent polymer nanoparticle that has an excitation peak at 383 nm and an emission peak at 476 nm, spectrally comparable to BV480. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ UV and Brilliant™ Violet.
StarBright Violet 475 (SBV475) is a fluorescent polymer nanoparticle that has an excitation peak at 383 nm and an emission peak at 476 nm, spectrally comparable to BV480. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ UV and Brilliant™ Violet.
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