CD4 StarBright Violet 475 (RM4-5, Rat) - Reactivity: Mouse
Product Details
| Description | Rat anti Mouse CD4:StarBright Violet 475 | |
|---|---|---|
| Conjugate | StarBright Violet 475 | |
| Clone | RM4-5 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Bio-Rad | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About StarBright Violet 475
StarBright Violet 475 (SBV475) is a fluorescent polymer nanoparticle that has an excitation peak at 383 nm and an emission peak at 476 nm, spectrally comparable to BV480. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ UV and Brilliant™ Violet.
StarBright Violet 475 (SBV475) is a fluorescent polymer nanoparticle that has an excitation peak at 383 nm and an emission peak at 476 nm, spectrally comparable to BV480. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ UV and Brilliant™ Violet.
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