CD45 Monoclonal / Brilliant Ultraviolet 737 / 30-F11

Product Details
Supplier Thermo Fisher Scientific
Catalog #: 367-0451-82 (View supplier product page)
Size 100 μg
Price $411.00
Antigen CD45
Clone 30-F11
Host Rat
Isotype IgG2b κ
Conjugate Brilliant Ultraviolet 737
Target Species Mouse
Applications FC
Description CD45 Monoclonal Antibody (30-F11), Brilliant Ultra Violet 737, eBioscience
About CD45 and Brilliant Ultraviolet 737
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Brilliant Ultraviolet 737 Brilliant™ UltraViolet 737 (BUV737) is a near infrared-emitting tandem fluorophore that combines BD Horizon® BUV395 and an acceptor dye. It can be excited by the 355 nm UV laser and collected using a 740/35 bandpass filter. BUV737 has an excitation peak at 498 nm and an emission peak at 732 nm This dye is part of the Brilliant™ UltraViolet dye family, developed and sold by BD Biosciences. This family of dyes uses BUV395 as the donor so that all dyes in the family can be excited by the 355 nm UV laser. Depending on the acceptor, the dyes in this family have different relative brightness ratings.
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Brilliant Ultraviolet 737 Excitation and Emission Spectra