Cytokeratin Acidic (Type I or LMW) / PerCP / SPM115

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-34393PCP (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen Cytokeratin Acidic (Type I or LMW)
Clone SPM115
Host Mouse
Isotype IgG1 κ
Conjugate PerCP
Target Species Bovine, Canine, Chicken, Human, Mouse, Primate, Rabbit, Rat, Reptile
Applications WB, FC, IHC-Fr, IHC-P, ICC/IF, IHC
Description This MAb recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50, 48, 46, 45, and 40kDa. MAb SPM116 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. SPM115/SPM116 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.
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PerCP Excitation and Emission Spectra