RBM8A / Unconjugated / PCRP-RBM8A-1B4

Product Details
Supplier Biorbyt
Catalog #: orb750823 (View supplier product page)
Size 100 μg
Price $693.60
Antigen RBM8A
Clone PCRP-RBM8A-1B4
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications
Description Mouse monoclonal antibody to RBM8A
About RBM8A and Purified
RBM8A This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus, although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing, including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present, thus coupling pre- and post-mRNA splicing events. Previously, it was thought that two genes encode this protein, RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene, which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome. [provided by RefSeq, Jul 2013]
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Purified Excitation and Emission Spectra