HIF-1 beta / DyLight 350 / H1beta234

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-124UV (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen HIF-1 beta
Clone H1beta234
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 350
Target Species Bovine, Ferret, Human, Mouse, Primate, Rat, Sheep
Applications WB, IHC-P, ICC/IF, IHC
About HIF-1 beta and DyLight 350
HIF-1 beta This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra