alpha 2 Macroglobulin / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb4268 (View supplier product page)
Size 100 μg
Price $567.80
Antigen alpha 2 Macroglobulin
Clone
Host Goat
Isotype IgG
Conjugate Biotin
Target Species Human
Applications ELISA, IF, WB
Description Goat polyclonal antibody against Human alpha 2 Macroglobulin conjugated to Biotin.
About alpha 2 Macroglobulin and Biotin
alpha 2 Macroglobulin The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
Citations
Additional
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Reviews & Ratings
Biotin Excitation and Emission Spectra