PLA2G4A / Unconjugated /

Product Details
Supplier Bethyl Laboratories
Catalog #: A305-205A-100UL (View supplier product page)
Size 100 μl
Price $424.00
Antigen PLA2G4A
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications WB, IP
Description Rabbit anti-PLA2G4A/cPLA2 Antibody, Affinity Purified
About PLA2G4A and Purified
PLA2G4A This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra