CBP / Unconjugated / RAB-C530

Product Details
Supplier Absolute Antibody
Catalog #: AB01766-10.6-BT-500UG (View supplier product page)
Size 500 μg
Price $3,141.00
Antigen CBP
Clone RAB-C530
Host Human
Isotype IgG
Conjugate Unconjugated
Target Species Human
Applications FC, IF
Description Anti CREBBP [RAB-C530]
About CBP and Purified
CBP This gene is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. The protein encoded by this gene has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain. Mutations in this gene cause Rubinstein-Taybi syndrome (RTS). Chromosomal translocations involving this gene have been associated with acute myeloid leukemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2009]
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Purified Excitation and Emission Spectra