IL-21 R / Unconjugated / ATR-107

Product Details
Supplier Absolute Antibody
Catalog #: AB01293-10.0-BT-1MG (View supplier product page)
Size 1 mg
Price $2,368.00
Antigen IL-21 R
Clone ATR-107
Host Human
Isotype IgG1
Conjugate Unconjugated
Target Species Human, Mouse, Non-Human Primate
Applications Block/Neutralize
Description Anti IL-21R [ATR-107]
About IL-21 R and Purified
IL-21 R The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2010]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra