UCP1 / DyLight 488 / 536435

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB6158K (View supplier product page)
Size 0.1 ml
Price $579.00
Antigen UCP1
Clone 536435
Host Mouse
Isotype IgG2b
Conjugate DyLight 488
Target Species Human, Mouse
Applications WB, ICFC, ICC
Description UCP1 Antibody (536435) [DyLight 488]
About UCP1 and DyLight 488
UCP1 Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq, Jul 2008]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra