RNF43 42694 ALWPWLLMAT (Dextramer) / APC / 923227R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB7964A (View supplier product page)
Size 0.1 ml
Price $579.00
Antigen RNF43 42694 ALWPWLLMAT (Dextramer)
Clone 923227R
Host Mouse
Isotype IgG1
Conjugate APC
Target Species Human
Applications FC
Description RNF43 Antibody (923227R) [Allophycocyanin]
About RNF43 42694 ALWPWLLMAT (Dextramer) and APC
RNF43 42694 ALWPWLLMAT (Dextramer) The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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APC Excitation and Emission Spectra