CD162 / HRP / 688101

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB9961H (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD162
Clone 688101
Host Mouse
Isotype IgG2a
Conjugate HRP
Target Species Human
Applications WB, IHC
Description PSGL-1/CD162 Antibody (688101) [HRP]
About CD162 and HRP
CD162 This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
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HRP Excitation and Emission Spectra