p53 / DyLight 594 / 261366

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB18391M (View supplier product page)
Size 0.1 ml
Price $539.00
Antigen p53
Clone 261366
Host Mouse
Isotype IgG1
Conjugate DyLight 594
Target Species Human
Applications ICFC, ICC
Description p53 [p Ser15] Antibody (261366) [DyLight 594]
About p53 and DyLight 594
p53 This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra