CD104 / DyLight 405 / 422325

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB4060E (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen CD104
Clone 422325
Host Mouse
Isotype IgG2b
Conjugate DyLight 405
Target Species Human
Applications WB, FC, ICC
Description Integrin beta 4/CD104 Antibody (422325) [DyLight 405]
About CD104 and DyLight 405
CD104 Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra