CD49b / Alexa Fluor 532 / 235033

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1740X (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen CD49b
Clone 235033
Host Rat
Isotype IgG2b
Conjugate Alexa Fluor 532
Target Species Mouse
Applications FC
Description Integrin alpha 2/CD49b Antibody (235033) [Alexa Fluor® 532]
About CD49b and Alexa Fluor 532
CD49b This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Alexa Fluor 532 Alexa Fluor™ 532 (AF532, Alexa 532) has an excitation peak at 532 nm and an emission peak at 554 nm, and is spectrally similar to Cy®3 (GE Healthcare), TRITC, iFluor® 514 (ATT Bioquest) and iFluor® 546 (ATT Bioquest). Many flow cytometers are equipped with 532nm lasers, so while Alexa 532 can be used for flow cytometry, PE is more commonly used due to its brightness and spectral characteristics. This dye is commonly used for fluorescence microscopy applications.
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Alexa Fluor 532 Excitation and Emission Spectra