CD85a / HRP / 222821

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1806H (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CD85a
Clone 222821
Host Mouse
Isotype IgG2a
Conjugate HRP
Target Species Human
Applications WB
Description ILT5/CD85a/LILRB3 Antibody (222821) [HRP]
About CD85a and HRP
CD85a This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
HRP Excitation and Emission Spectra