IL-10 R alpha / HRP / 714212
IL-10 R alpha / HRP / 714212
Product Details
| Supplier | Novus Biologicals, a Bio-Techne brand | |
|---|---|---|
| Catalog #: | FAB2742H (View supplier product page) | |
| Size | 0.1 ml | |
| Price | $539.00 | |
| Antigen | IL-10 R alpha | |
| Clone | 714212 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | HRP | |
| Target Species | Human | |
| Applications | WB | |
| Description | IL-10R alpha Antibody (714212) [HRP] |
About IL-10 R alpha and HRP
| IL-10 R alpha | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009] |
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Citations
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Reviews & Ratings
HRP Excitation and Emission Spectra
$539.00
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