CD45 Monoclonal / Brilliant Violet 570 / 30-F11

Product Details
Supplier Sony
Catalog #: 1115675 (View supplier product page)
Size 125 μl
Price $220.00
Antigen CD45
Clone 30-F11
Host Rat
Isotype IgG2b κ
Conjugate Brilliant Violet 570
Target Species Mouse
Applications FC
Description Brilliant Violet 570 anti-mouse CD45
About CD45 and Brilliant Violet 570
CD45 The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Brilliant Violet 570 Brilliant™ Violet 570 (BV570) is a yellow-emitting tandem fluorophore that can be excited by the 405 nm Violet laser and collected using a 585/42 bandpass filter. BV570 has an excitation peak at 405 nm and an emission peak at 570 nm, and is spectrally similar to StarBright 570 (Bio-Rad). This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dye from Beckman Coulter and StarBright dyes from Bio-Rad.
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Brilliant Violet 570 Excitation and Emission Spectra