CD357 / DyLight 594 / 2375B

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB52412M (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen CD357
Clone 2375B
Host Rabbit
Isotype IgG
Conjugate DyLight 594
Target Species Mouse
Applications FC, IHC, ICC
Description GITR/TNFRSF18 Antibody (2375B) [DyLight 594]
About CD357 and DyLight 594
CD357 This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra