GFR alpha-2 / DyLight 488 / 71515

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB6131K (View supplier product page)
Size 0.1 ml
Price $539.00
Antigen GFR alpha-2
Clone 71515
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications FC, ICC
Description GFR alpha-2/GDNF R alpha-2 Antibody (71515) [DyLight 488]
About GFR alpha-2 and DyLight 488
GFR alpha-2 Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra