GDF-15 / DyLight 650 / 7C12.B3.F2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-42725C (View supplier product page)
Size 0.1 ml
Price $659.00
Antigen GDF-15
Clone 7C12.B3.F2
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 650
Target Species Human
Applications WB, ELISA
Description GDF-15 Antibody (7C12.B3.F2) [DyLight 650]
About GDF-15 and DyLight 650
GDF-15 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra