GAPDH / Alexa Fluor 594 / 13H12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-27103AF594 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen GAPDH
Clone 13H12
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 594
Target Species Drosophila, Human, Monkey, Mouse, Primate, Rat, Sheep
Applications WB, IHC, ICC/IF, IHC-P
Description GAPDH Antibody (13H12) [Alexa Fluor® 594]
About GAPDH and Alexa Fluor 594
GAPDH This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra