CD105 / Janelia Fluor 549 / 209701

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1320I (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CD105
Clone 209701
Host Rat
Isotype IgG2a
Conjugate Janelia Fluor 549
Target Species Mouse
Applications WB, FC, IHC, ICC
Description Endoglin/CD105 Antibody (209701) [Janelia Fluor® 549]
About CD105 and Janelia Fluor 549
CD105 This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra