CX3CL1 / Janelia Fluor 549 / 126315

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB571I (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CX3CL1
Clone 126315
Host Rat
Isotype IgG2a
Conjugate Janelia Fluor 549
Target Species Mouse
Applications WB, ELISA
Description CX3CL1/Fractalkine Antibody (126315) [Janelia Fluor® 549]
About CX3CL1 and Janelia Fluor 549
CX3CL1 This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra