Coagulation Factor VII / DyLight 350 / 321605

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB23381D (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen Coagulation Factor VII
Clone 321605
Host Mouse
Isotype IgG2b
Conjugate DyLight 350
Target Species Human
Applications FC
Description Coagulation Factor VII Antibody (321605) [DyLight 350]
About Coagulation Factor VII and DyLight 350
Coagulation Factor VII This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides. [provided by RefSeq, Aug 2015]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra