C-Myc / Alexa Fluor 350 / MYC909

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-86683AF350 (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen C-Myc
Clone MYC909
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 350
Target Species Human
Applications FC, IHC, ICC/IF, IHC-P, IF
Description c-Myc Antibody (MYC909) [Alexa Fluor® 350]
About C-Myc and Alexa Fluor 350
C-Myc This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra