CD59 / DyLight 350 / 2491C

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1987D (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CD59
Clone 2491C
Host Rabbit
Isotype IgG
Conjugate DyLight 350
Target Species Human
Applications FC
Description CD59 Antibody (2491C) [DyLight 350]
About CD59 and DyLight 350
CD59 This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra