CD30L / DyLight 405 / 116614

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1028E (View supplier product page)
Size 0.1 ml
Price $559.00
Antigen CD30L
Clone 116614
Host Mouse
Isotype IgG2b
Conjugate DyLight 405
Target Species Human
Applications FC
Description CD30 Ligand/TNFSF8 Antibody (116614) [DyLight 405]
About CD30L and DyLight 405
CD30L The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra