CD177 / DyLight 594 / 1171A

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB8186M (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD177
Clone 1171A
Host Rabbit
Isotype IgG
Conjugate DyLight 594
Target Species Mouse
Applications FC
Description CD177 Antibody (1171A) [DyLight 594]
About CD177 and DyLight 594
CD177 This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
DyLight 594 DyLight™ 594 has an excitation peak at 593 nm and an emission peak at 618 nm and is spectrally similar to Alexa Fluor™ 594 and Texas Red. DyLight™ 594 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 594 Excitation and Emission Spectra