CD11b / DyLight 488 / 908649

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB11241K (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CD11b
Clone 908649
Host Rat
Isotype IgG2b
Conjugate DyLight 488
Target Species Mouse
Applications WB, FC
Description CD11b Antibody (908649) [DyLight 488]
About CD11b and DyLight 488
CD11b This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra