CCR10 / Biotin / 314305R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB3478RB (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CCR10
Clone 314305R
Host Rat
Isotype IgG2a
Conjugate Biotin
Target Species Human
Applications FC
Description CCR10/GPR2 Antibody (314305R) [Biotin]
About CCR10 and Biotin
CCR10 Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).[supplied by OMIM, Mar 2008]
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Biotin Excitation and Emission Spectra