BMPR-IB / DyLight 405 / 477914

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB5051E (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen BMPR-IB
Clone 477914
Host Mouse
Isotype IgG2b
Conjugate DyLight 405
Target Species Human
Applications FC, ICC
Description BMPR-IB/ALK-6 Antibody (477914) [DyLight 405]
About BMPR-IB and DyLight 405
BMPR-IB This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
Citations
Additional
Sources
Reviews & Ratings
DyLight 405 Excitation and Emission Spectra