Bcl-6 / Janelia Fluor 646 / rBCL6/1475

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP3-08835JF646 (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen Bcl-6
Clone rBCL6/1475
Host Mouse
Isotype IgG1 κ
Conjugate Janelia Fluor 646
Target Species Human
Applications WB
Description Bcl-6 Antibody (rBCL6/1475) [Janelia Fluor® 646]
About Bcl-6 and Janelia Fluor 646
Bcl-6 The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]
Janelia Fluor 646 Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.
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Janelia Fluor 646 Excitation and Emission Spectra