CD276 / DyLight 488 / 185504

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: FAB1027K (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen CD276
Clone 185504
Host Mouse
Isotype IgG1
Conjugate DyLight 488
Target Species Human
Applications WB, FC, Knockout Validated
Description B7-H3/CD276 Antibody (185504) [DyLight 488]
About CD276 and DyLight 488
CD276 The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
DyLight 488 DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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DyLight 488 Excitation and Emission Spectra